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AII-1001-99999
ConfirmedA court, a regulator or the organization itself has stated the core facts, or the record cites a court or regulator source.Supporting sources are pending verification.

OpenAI warns future ChatGPT models pose higher bioweapons creation risk

OpenAI said its next-generation AI models could significantly increase the risk of biological weapon development, including enabling individuals with limited scientific expertise to create dangerous agents. The company is increasing safety testing and expects some successor models to its o3 reasoning system to reach its highest risk classification tier.

19 June 2025 Β· OpenAI Β· Security and cyberattacks
19 June 2025
AII-1001-99999
Quick facts
Organization
OpenAI (subject)
Category
Security and cyberattacks
Country
United States
Date
19 June 2025
Drafted by
Raidu Incident Detection

What happened

OpenAI warned that its next generation of advanced AI models could pose a significantly higher risk of biological weapon development, particularly when used by individuals with little scientific expertise.

OpenAI executives told Axios the company anticipates upcoming models will trigger the high-risk classification under its preparedness framework, with head of safety systems Johannes Heidecke stating the company is 'expecting some of the successors of our o3 (reasoning model) to hit that level.'

Reported impact

OpenAI expressed concern that without mitigations, models will soon be capable of 'novice uplift,' allowing those with limited scientific knowledge to create dangerous weapons.

The company said it is increasing its safety testing to mitigate the risk that models will help users in the creation of biological weapons.

Index analysis

OpenAI stated it has a strategy in place to deploy guardrails that prevent ChatGPT from helping bad actors when given harmful prompts, and has engaged with biosecurity, bioweapons, and bioterrorism experts.

Governance controls

OpenAI is boosting its safety testing as it anticipates some models will reach its highest risk tier.

The company developed a preparedness framework designed to evaluate and mitigate risks posed by increasingly powerful AI models.

Classification

Organization
OpenAI (subject)
Category
Security and cyberattacks
Industry
Healthcare, drugs and biotechnology
Country
United States
Harm status
Potential harm
Intent
Unintentional
Timing
Unknown
Harm types
Public interest
Harmed
General public
Consequences
None recorded
AI systems
ChatGPT, OpenAI o3

Sources and evidence

Sources not yet published

This record was researched and written by the Index from original reporting. Its sources are still being verified by an editor, and they are listed here once that check is complete. Until then the record carries no reviewer.

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